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Baseline neutrophil-to-lymphocyte ratio predicts response to corticosteroids and is associated with infection and renal dysfunction in alcoholic hepatitis.

Ewan H ForrestNatasha StoreyRohit SinhaStephen R AtkinsonNikhil VergisPaul RichardsonSteven MassonStephen RyderMark R ThurszMichael AllisonAndrew FraserAndrew AustinAnne McCuneAshwin D DhandaDev KatareyJonathan PottsSumita VermaRichard ParkerPeter C Hayesnull null
Published in: Alimentary pharmacology & therapeutics (2019)
The NLR is associated with AKI and infection in severe alcoholic hepatitis. The NLR identifies those most likely to benefit from corticosteroids at baseline (NLR 5-8). The mGAHS has a good predictive value for 28- and 90-day outcomes.
Keyphrases
  • liver injury
  • drug induced
  • acute kidney injury
  • oxidative stress
  • early onset
  • dna methylation
  • metabolic syndrome
  • skeletal muscle
  • insulin resistance