Baseline neutrophil-to-lymphocyte ratio predicts response to corticosteroids and is associated with infection and renal dysfunction in alcoholic hepatitis.
Ewan H ForrestNatasha StoreyRohit SinhaStephen R AtkinsonNikhil VergisPaul RichardsonSteven MassonStephen RyderMark R ThurszMichael AllisonAndrew FraserAndrew AustinAnne McCuneAshwin D DhandaDev KatareyJonathan PottsSumita VermaRichard ParkerPeter C Hayesnull nullPublished in: Alimentary pharmacology & therapeutics (2019)
The NLR is associated with AKI and infection in severe alcoholic hepatitis. The NLR identifies those most likely to benefit from corticosteroids at baseline (NLR 5-8). The mGAHS has a good predictive value for 28- and 90-day outcomes.