Methylation status of genes escaping from X-chromosome inactivation in patients with X-chromosome rearrangements.

Sayaka KawashimaAtsushi HattoriErina SuzukiKeiko MatsubaraMachiko TokiRika KosakiYukihiro HasegawaKazuhiko NakabayashiMaki FukamiMasayo Kagami

Published in: Clinical epigenetics (2021)

X-chromosome rearrangements are unlikely to affect the methylation status of the promoter regions of escape genes, except for a specific case with highly complex rearrangements, including the deletion of the FIRRE gene and the duplication of DXZ4.

Keyphrases

genome wide
copy number
dna methylation
genome wide identification
gene expression
transcription factor
genome wide analysis
bioinformatics analysis