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Cytokine Profiles as Potential Prognostic and Therapeutic Markers in SARS-CoV-2-Induced ARDS.

Francesco SaltonPaola ConfalonieriGiuseppina CampiscianoRossella CifaldiClara RizzardiDaniele GeneraliRiccardo PozzanStefano TavanoChiara BozziGiulia LapadulaGianfranco Umberto MeduriMarco ConfalonieriManola ComarSelene LerdaBarbara Ruaro
Published in: Journal of clinical medicine (2022)
Patients in the IMV group had higher inflammation levels at intubation than the NIV group, which may indicate a higher resistance to glucocorticoids. Higher GC doses or a longer treatment duration in these patients might have allowed for a better control of inflammation and a better outcome. Further studies are required to define the prognostic value of cytokine patterns, in terms of both GC treatment tailoring and timely initiation of IMV.
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