Weak circadian rhythm increases neutropenia risk among breast cancer patients undergoing adjuvant chemotherapy.
Wentao LiCarol Chi-Hei KwokDominic Chun-Wan ChanFeng WangLap Ah TsePublished in: Breast cancer research and treatment (2017)
This study provides the first epidemiological evidence that increased risks of grade 4 neutropenia and febrile neutropenia are associated with weak circadian rhythm among adjuvant breast cancer patients. The results suggest that circadian rhythm might be one potential target for the prevention of chemotherapy-induced neutropenia among cancer patients.