Multiomics Analysis of Genetics and Epigenetics Reveals Pathogenesis and Therapeutic Targets for Atrial Fibrillation.

Li Liu Jianjun HuangBaomin WeiJianjiao MoQinjiang WeiChengcai ChenWei YanXiannan HuangFengzhen HeLingling QinHehua HuangXue LiXingshou Pan

Published in: BioMed research international (2021)

Our findings identified DEGs related to DNA methylation and mutation for AF, which may offer possible therapeutic targets and a new insight into the pathogenesis of AF from a multiomics perspective.

Keyphrases

atrial fibrillation
dna methylation
oral anticoagulants
catheter ablation
left atrial
left atrial appendage
direct oral anticoagulants
heart failure
genome wide
gene expression
percutaneous coronary intervention
acute coronary syndrome
left ventricular
mitral valve