Fabrication of pH responsive hydrogel blends of chondroitin sulfate/pluronic F-127 for the controlled release of ketorolac: its characterization and acute oral toxicity study.

Saba NaeemKashif BarkatMaryam ShabbirIkrima KhalidIrfan AnjumNadia ShamshadYasir MehmoodDaulat Haleem KhanSyed Faisal Badshah Muhammad Ali SyedSana AfzalZainab Abdullah

Published in: Drug development and industrial pharmacy (2022)

The prepared CS/Pl hydrogels demonstrated stimuli-controlled release with delivery of drug for prolonged period of time and thus can minimize dosing frequency, safe drug delivery, increased patient compliance and easiness.

Keyphrases

drug delivery
hyaluronic acid
tissue engineering
cancer therapy
drug release
liver failure
case report
respiratory failure
emergency department
wound healing
intensive care unit
low cost
acute respiratory distress syndrome
extracorporeal membrane oxygenation