Fabrication of pH responsive hydrogel blends of chondroitin sulfate/pluronic F-127 for the controlled release of ketorolac: its characterization and acute oral toxicity study.
Saba NaeemKashif BarkatMaryam ShabbirIkrima KhalidIrfan AnjumNadia ShamshadYasir MehmoodDaulat Haleem KhanSyed Faisal BadshahMuhammad Ali SyedSana AfzalZainab AbdullahPublished in: Drug development and industrial pharmacy (2022)
The prepared CS/Pl hydrogels demonstrated stimuli-controlled release with delivery of drug for prolonged period of time and thus can minimize dosing frequency, safe drug delivery, increased patient compliance and easiness.