Contemporary lipid-lowering management and risk of cardiovascular events in homozygous familial hypercholesterolaemia: insights from the Italian LIPIGEN Registry.

Laura D'ErasmoSimone BiniManuela CasulaMarta GazzottiStefano BertoliniSebastiano CalandraPatrizia TarugiMaurizio Rocco AvernaGabriella IannuzzoGiuliana FortunatoAlberico L CatapanoMarcello Arcanull null

Published in: European journal of preventive cardiology (2024)

Our findings indicate that the combination of novel and conventional LLTs significantly improved LDL-C control with a signal of better cardiovascular prognosis in HoFH patients. Overall, these results advocate the use of intensive, multidrug LLTs to effectively manage HoFH.

Keyphrases

cardiovascular events
end stage renal disease
coronary artery disease
ejection fraction
chronic kidney disease
cardiovascular disease
drug resistant
prognostic factors
early onset
patient reported outcomes
patient reported