Impact of Genetic polymorphisms on the risk of epilepsy amongst patients with acute brain injury: a systematic review.

Shubham Misra Terence Joseph QuinnGuido J FalconeVijay Kumar SharmaAdam de HavenonYize ZhaoEce EldemJacqueline A FrenchClarissa Lin YasudaJesse DawsonDavid S LiebeskindPatrick KwanNishant K Mishra

Published in: European journal of neurology (2023)

The current evidence on the association of genetic polymorphisms in epilepsy secondary to TBI or stroke is of low quality and lacks validation. A collaborative effort to pool genetic data linked to epileptogenesis in stroke and TBI patients is warranted.

Keyphrases

brain injury
traumatic brain injury
subarachnoid hemorrhage
atrial fibrillation
cerebral ischemia
end stage renal disease
ejection fraction
newly diagnosed
prognostic factors
quality improvement
peritoneal dialysis
electronic health record
genome wide
gene expression
copy number
patient reported outcomes