Clinical Application of ISO and CEN/TS Standards for Liquid Biopsies-Information Everybody Wants but Nobody Wants to Pay For.
Lilli BonstinglChristina SkoflerChristine UlzMargret ZinneggerKatja SallingerJulia SchönbergerKatharina SchuchKarin PankratzAnatol Borrás-CherrierVisnja SomodiPeter M AbujaLisa Oberauner-WappisTina MoserEllen HeitzerThomas BauernhoferThomas KroneisAmin El-HeliebiPublished in: Clinical chemistry (2024)
Our study demonstrates the feasibility and benefits of adhering to ISO and CEN/TS standards in a clinical liquid biopsy study. The standards revealed that hemolysis occurred frequently but did not impair downstream ctDNA and CTC analysis in our cohort of advanced prostate cancer patients.