Identification, characterization and epitope mapping of proteins encoded by putative allergenic napin genes from Brassica rapa.

Mahmudur RahmanAbdul BatenRamil MauleonGraham J KingLei LiuBronwyn J Barkla

Published in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2020)

Napin is thought to be responsible for a high prevalence of food allergies. Characterization of the napin gene family in B rapa will give important insight into the protein structure, and epitope modelling will help to advance studies into allergenicity including the development of precise diagnostic screenings and therapies for this potential food allergy as well as the possible manipulation of napin levels in the seed by gene editing technology.

Keyphrases

genome wide analysis
bioinformatics analysis
human health
monoclonal antibody
genome wide identification
high resolution
genome wide
risk assessment
protein protein
gene expression
case control
dna methylation
amino acid