Iron-catalyzed aerobic oxidation of silyl ethers to carboxylic acids.

Published in: Chemical communications (Cambridge, England) (2024)

Direct aerobic oxidation of silyl ethers to carboxylic acids has been developed. The mild reaction conditions lead to a broad range of functional group compatibility. Different types of silyl groups have been investigated and selective deprotective oxidation has been realized. The reaction could be conducted under air.

Keyphrases

electron transfer
hydrogen peroxide
high intensity
visible light
atomic force microscopy
iron deficiency