No evidence for causal effects of C-reactive protein (CRP) on chronic pain conditions: a Mendelian randomization study.

Pradeep SuriYakov A TsepilovElizaveta E ElgaevaFrances M K WilliamsMaxim B FreidinIan B Stanaway

Published in: medRxiv : the preprint server for health sciences (2024)

This MR study found no causal association of CRP on spinal pain, the extent of chronic pain, or chronic widespread pain. Future studies examining mechanistic biomarkers for pain conditions should consider other candidates besides CRP.

Keyphrases

chronic pain
pain management
neuropathic pain
spinal cord
magnetic resonance
computed tomography
magnetic resonance imaging
current status
drug induced