A cysteine-selective fluorescent probe for monitoring stress response cysteine fluctuations.

Yang YangLiangwei ZhangXia ZhangShudi LiuYue WangLi ZhangZhuo MaHuiyan YouLingxin Chen

Published in: Chemical communications (Cambridge, England) (2021)

Rare studies provided evidence for the real-time monitoring of stress response cysteine fluctuations. Here, we have successfully designed and synthesized a cysteine-selective fluorescent probe 1 to monitor stress response Cys fluctuations, providing visual evidence of Hg2+ regulated cysteine fluctuations for the first time, which may open a new way to help researchers to reveal the mechanism of heavy metal ion poisoning.

Keyphrases

fluorescent probe
living cells
heavy metals
minimally invasive
risk assessment
gene expression
genome wide