Enhancement of Cancer Chemotherapeutic Efficacy via Bone-Targeted Drug Delivery Carrier in Bone Metastases.

Xinghe XueJiachen YuFengfeng LuHongyi JiangXiang-Yang Wang

Published in: Drug design, development and therapy (2021)

Our study confirmed that Aln-MOF has good stability, bone targeting and biosafety. Aln-MOFDOX could release DOX and effectively kill tumor cells of bone metastases. Aln-MOFDOX has a promising prospect in the treatment of bone metastasis.

Keyphrases

bone mineral density
drug delivery
cancer therapy
soft tissue
bone loss
bone regeneration
postmenopausal women
squamous cell carcinoma
young adults
smoking cessation