Liquid biopsy: an examination of platelet RNA obtained from head and neck squamous cell carcinoma patients for predictive molecular tumor markers.

Lisa T Huber Johann M KrausJasmin EzićAmin Wanli Marco Groth Simon LabanThomas K HoffmannBarbara Wollenberg Hans Armin Kestler Cornelia Brunner

Published in: Exploration of targeted anti-tumor therapy (2023)

These results indicate a transfer of tumor-derived messenger RNA (mRNA) into platelets of HNSCC patients. Therefore, analyses of a patient's platelet RNA could be an efficient option for liquid biopsy in order to diagnose HNSCC or to monitor tumorigenesis as well as therapeutic responses at any time and in real time.

Keyphrases

end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
prognostic factors
ionic liquid
case report
nucleic acid
patient reported