Incentives conditioned on tenofovir levels to support PrEP adherence among young South African women: a randomized trial.
Connie L CelumKatherine GillJennifer F MortonGabrielle SteinLaura MyersKatherine K ThomasMargaret McConnellAriane van der StratenJared M BaetenMenna DuyverEve MendelKeshani NaidooJacqui DallimoreLubbe WiesnerLinda Gail BekkerPublished in: Journal of the International AIDS Society (2021)
Among South African AGYW initiating PrEP, drug levels indicated high PrEP adherence in almost half of women at Month 3, with a non-statistically significant higher proportion with high adherence among those in the incentive group. Over half persisted with the 12-month PrEP programme although high adherence declined after Month 3. Strategies to support PrEP adherence and persistence and longer-acting PrEP formulations are needed.