Behavioral and Molecular Analysis of Antioxidative Potential of Rosmarinic Acid Against Methamphetamine-induced Augmentation of Casp3a mRNA in the Zebrafish Brain.
Vida Nikshenas ShahrestaniMohammad HaddadiAli Reza Samzadeh KermaniPublished in: Basic and clinical neuroscience (2021)
The potential of RA combined with a suitable nanoparticle against MA-induced oxidative stress was supported. The high efficiency of ZnO/chitosan in increasing RA penetration to the brain cells was evident. MA at a dose of 25 mg/L is anxiolytic for zebrafish. However, the molecular mechanisms involved in these processes should be studied.
Keyphrases
- high efficiency
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- cell cycle arrest
- ankylosing spondylitis
- cerebral ischemia
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- stress induced