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Efficacy and safety of a new ranibizumab biosimilar CKD-701 using a pro re nata treatment regimen in neovascular age-related macular degeneration: A phase 3 randomized clinical trial.

Chang Ki YoonJaeryung OhKunho BaeUn Chul ParkKyung-Sang YuHyeong Gon Yu
Published in: PloS one (2022)
CKD-701 is a biosimilar to the reference ranibizumab in terms of efficacy, safety, and immunogenicity for the treatment of patients with nAMD. Moreover, improvement and maintenance of visual outcome were achieved through PRN regimen.
Keyphrases
  • age related macular degeneration
  • chronic kidney disease
  • diabetic retinopathy
  • clinical trial
  • combination therapy
  • endothelial cells
  • optical coherence tomography
  • replacement therapy
  • double blind