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Reverse Dynamization Accelerates Bone-Healing in a Large-Animal Osteotomy Model.

Vaida GlattMikhail SamchukovAlexander CherkashinChristopher A Iobst
Published in: The Journal of bone and joint surgery. American volume (2021)
This study demonstrates that the concept of reverse dynamization challenges the current understanding regarding the optimal fixation stability necessary to maximize the regenerative capacity of bone-healing. When reverse dynamization is employed in the clinical setting, it may be able to improve the treatment of fractures by reducing the time to union and potentially lowering the risk of delayed union and nonunion.
Keyphrases
  • bone mineral density
  • stem cells
  • mesenchymal stem cells
  • bone loss
  • total knee arthroplasty
  • minimally invasive
  • cell therapy
  • body composition
  • combination therapy
  • bone marrow
  • replacement therapy
  • tissue engineering