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Genetic analyses implicate complex links between adult testosterone levels and health and disease.

Jaakko T LeinonenNina J MarsLeevi E LehtonenAri Ahola-OlliSanni E RuotsalainenTerho LehtimäkiMika KähönenOlli Raitakarinull nullAnnemieke HoekMark DalyTiinamaija TuomiSamuli RipattiMatti PirinenTaru Tukiainen
Published in: Communications medicine (2023)
Overall, these findings provide insight into how genetically determined testosterone correlates with several health parameters in both sexes. Yet the lack of evidence for a causal contribution to most traits beyond sex-specific health underscores the complexity of the mechanisms linking testosterone levels to disease risk and sex differences.
Keyphrases
  • public health
  • healthcare
  • mental health
  • replacement therapy
  • health information
  • genome wide
  • health promotion
  • gene expression
  • dna methylation
  • social media