Genetic analyses implicate complex links between adult testosterone levels and health and disease.
Jaakko T LeinonenNina J MarsLeevi E LehtonenAri Ahola-OlliSanni E RuotsalainenTerho LehtimäkiMika KähönenOlli Raitakarinull nullAnnemieke HoekMark DalyTiinamaija TuomiSamuli RipattiMatti PirinenTaru TukiainenPublished in: Communications medicine (2023)
Overall, these findings provide insight into how genetically determined testosterone correlates with several health parameters in both sexes. Yet the lack of evidence for a causal contribution to most traits beyond sex-specific health underscores the complexity of the mechanisms linking testosterone levels to disease risk and sex differences.