Maternal Calorie Restriction Induces a Transcriptional Cytoprotective Response in Embryonic Liver Partially Dependent on Nrf2.

George I HabeosFotini FilippopoulouEvagelia E HabeosElectra Kalaitzopoulou Marianna Skipitari Polyxeni Papadea George LagoumintzisAthanasios NiarchosChristos D Georgiou Dionysios V Chartoumpekis

Published in: Antioxidants (Basel, Switzerland) (2022)

Calorie restriction during pregnancy elicits the transcriptional induction of cytoprotective/antioxidant genes in the fetal liver, which is at least partially Nrf2-dependent, with a physiological significance that warrants further investigation.

Keyphrases

oxidative stress
weight loss
gene expression
transcription factor
heat shock
genome wide
birth weight
pregnant women
anti inflammatory
body mass index
weight gain
preterm birth
heat shock protein