The Integrin Inhibitor Cilengitide and Bleomycin-Induced Pulmonary Fibrosis : Cilengitide and Bleomycin-Induced Pulmonary Fibrosis.

Jeffrey D RitzenthalerMichael ZhangEdilson Torres-GonzalezJesse Roman

Published in: Lung (2020)

Overall, our data suggest that, despite its in vitro activity in fibroblasts, daily injections of cilengitide (20 mg/kg) did not inhibit the development of or ameliorate bleomycin-induced pulmonary fibrosis in mice.

Keyphrases

pulmonary fibrosis
high glucose
diabetic rats
drug induced
physical activity
machine learning
adipose tissue
insulin resistance
extracellular matrix
platelet rich plasma