Copper-mediated β-amyloid toxicity and its chelation therapy in Alzheimer's disease.

Sandeep Kumar SinghVyshnavy BalendraAhmad A ObaidJosephine EspostoMaria A TikhonovaNaveen Kumar GautamBurkhard Poeggeler

Published in: Metallomics : integrated biometal science (2022)

Authors explore copper ion interaction w/Aβ and kinetics of fibril formation in promoting amyloid-β mediated cell toxicity in Alzheimer's disease and the potential use of copper chelators in the prevention of copper-mediated Aβ toxicity.

Keyphrases

oxide nanoparticles
oxidative stress
cognitive decline
cell therapy
stem cells
risk assessment
mesenchymal stem cells
climate change
human health
replacement therapy