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Pooled safety analysis of tisagenlecleucel in children and young adults with B cell acute lymphoblastic leukemia.

John E LevineStephan A GruppMichael A PulsipherAndrew C DietzSusana RivesG Douglas MyersKeith J AugustMichael R VernerisJochen BuechnerTheodore W LaetschHenrique BittencourtAndre BaruchelMichael W BoyerBarbara De MoerlooseMuna QayedStella M DaviesChristine L PhillipsTimothy A DriscollPeter BaderKrysta SchlisPatricia A WoodRajen ModyLan YiMimi LeungLamis K EldjerouCarl H JuneShannon L Maude
Published in: Journal for immunotherapy of cancer (2022)
This pooled analysis provides a detailed safety profile for tisagenlecleucel during the course of clinical trials, and AE management guidance, with a longer follow-up duration compared with previous reports.
Keyphrases
  • acute lymphoblastic leukemia
  • clinical trial
  • young adults
  • allogeneic hematopoietic stem cell transplantation
  • adverse drug
  • phase ii
  • open label
  • electronic health record