Weight Loss Following Roux-en-Y Gastric Bypass Causally Implicated with Serum Levels of IL-22: A Mendelian Randomization and Phenome-Wide Association Study.

Published in: Obesity (Silver Spring, Md.) (2021)

Weight loss following RYGB may cause an increase in IL-22 serum levels, suggesting that weight loss directly contributes to immune modulation following bypass. These results demonstrate the utility of genetic studies to disentangling molecular cause and effect following bariatric surgery.

Keyphrases

weight loss
roux en y gastric bypass
bariatric surgery
gastric bypass
obese patients
glycemic control
weight gain
genome wide
single molecule
insulin resistance