Green Formulation of Spironolactone Loaded Chitosan-Coated Nano Lipid Carrier for Treatment of Acne Vulgaris: A Randomized Double-Blind Clinical Trial.

Majid SaeediKatayoun Morteza-SemnaniJafar AkbariZohreh HajheydariAmin GoodarziSeyyed Sohrab RostamkalaeiSeyyed Mohammad Hassan Hashemi Seyyed Mobin Rahimnia

Published in: Advanced pharmaceutical bulletin (2023)

The findings indicate that chitosan-coated SPN-NLCs have the potential as nanoparticles for targeted SPN delivery to the skin, offering novel options for the treatment of acne vulgaris.

Keyphrases

drug delivery
clinical trial
double blind
cancer therapy
study protocol
phase ii
risk assessment
open label
combination therapy
replacement therapy
climate change
human health
smoking cessation