Axonal transport in a peripheral diabetic neuropathy model: sex-dimorphic features.
Marzia PesaresiSilvia GiattiRoberto SpezzanoSimone RomanoSilvia DiviccaroTiziana BorselloNico MitroDonatella CarusoLuis Miguel Garcia-SeguraRoberto Cosimo MelcangiPublished in: Biology of sex differences (2018)
These findings suggest that sex-specific decrease in neuroactive steroid levels in male diabetic animals may cause an alteration in their mitochondrial function that in turn might impact in axonal transport, contributing to the sex difference observed in diabetic neuropathy.