Automated Synthesis of [ 11 C]PiB via [ 11 CH 3 OTf]-as Methylating Agent for PET Imaging of β-Amyloid.

C]PiB. The final HPLC-free purification yielded more than 97% radiochemical purity tracer within one radionuclide half-life. The method was reproducible and efficient for any clinical center.