Temporal characteristics of astrocytic activation in the TNC in a mice model of pain induced by recurrent dural infusion of inflammatory soup.

Leyi ZhangChenglong LuLi KangYingji LiWenjing TangDengfa ZhaoShengyuan YuRuozhuo Liu

Published in: The journal of headache and pain (2022)

Our results indicate that the astrocytic activation generated and sustained in the IS-induced mice model from 1 d to 28 d after the last infusion and may contribute to the pathology through modulating CCL7, CCL12, and IL-10 release.

Keyphrases

high fat diet induced
liver injury
low dose
drug induced
chronic pain
liver fibrosis
high glucose
pain management
neuropathic pain
type diabetes
diabetic rats
spinal cord injury
skeletal muscle
postoperative pain