Age Differences in Comorbidities, Presenting Symptoms, and Outcomes of Influenza Illness Requiring Hospitalization: A Worldwide Perspective From the Global Influenza Hospital Surveillance Network.
Melissa K AndrewHenrique PottLisa StaadegaardJohn PagetSandra S ChavesJustin R OrtizJohn McCauleyJoseph BreseeMarta C NunesElsa BaumeisterSonia Mara RaboniHeloisa I G GiamberardinoShelly A McNeilDoris GomezTao ZhangPhilippe VanhemsParvaiz A KoulDaouda CoulibalyNancy A OtienoGhassan DbaiboMaria Lourdes Guerrero AlmeidaVictor Alberto Laguna-TorresAnca Cristina DrăgănescuElena BurtsevaAnna SomininaDaria DanilenkoSnežana MedićJavier Diez-DomingoBruno LinaPublished in: Open forum infectious diseases (2023)
Both virus and host factors contributed to influenza burden. We identified age differences in comorbidities, presenting symptoms, and adverse clinical outcomes among those hospitalized with influenza and benefit from influenza vaccination in protecting against adverse clinical outcomes. The GIHSN provides an ongoing platform for global understanding of hospitalized influenza illness.