Acute and chronic toxicity of deltamethrin, permethrin, and dihaloacetylated heterocyclic pyrethroids in mice.
Qiuyan ZhuYang YangZhiting LaoYingying ZhongKun ZhangSuqing ZhaoPublished in: Pest management science (2020)
Pyrethroids exposure induced weight loss in mice, although the acute oral toxicity of deltamethrin, permethrin and dihaloacetylated heterocyclic pyrethroids DCA-O, DCA-01, and DCA-11 was low. However, regarding chronic toxicity, deltamethrin, permethrin and dihaloacetylated heterocyclic pyrethroids DCA-O, DCA-01, and DCA-11 induced anxiety-like behaviors, excitatory behaviors, Gln-Glu-GABA circulatory dysfunction in blood. Particularly, deltamethrin, though permethrin also had reproductive toxicity. © 2020 Society of Chemical Industry.
Keyphrases
- drug induced
- oxidative stress
- diabetic rats
- aedes aegypti
- liver failure
- weight loss
- high glucose
- respiratory failure
- high fat diet induced
- bariatric surgery
- extracorporeal membrane oxygenation
- aortic dissection
- hepatitis b virus
- insulin resistance
- metabolic syndrome
- endothelial cells
- adipose tissue
- physical activity