The antiherpetic and anti-inflammatory activity of the frog-derived peptide Hylin-a1.
Annalisa ChianeseRosa GiuglianoFrancesca PalmaBianca M NastriAlessandra MontiNunzianna DotiCarla ZannellaMassimiliano GaldieroAnna De FilippisPublished in: Journal of applied microbiology (2024)
The data presented in this study, such as the increased activity of the peptide when combined to acyclovir, a weak hemolytic profile, an anti-inflammatory effect, and a tolerable half-life in serum, indicates Hylin-a1 as a novel antiherpetic molecule with promising potential in the clinical setting.