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Potential in vitro anti-allergic, anti-inflammatory and cytotoxic activities of ethanolic extract of Baliospermum montanum root, its major components and a validated HPLC method.

Weerachai PipatrattanasereeArunporn ItharatNichamon MukkasombutUbonwan Saesiw
Published in: BMC complementary and alternative medicine (2019)
The results of this study suggested that ethanolic extract of of B.montanum root can be a potential source of anti-allergy, anti-inflammation, and anti-cancer compounds. The isolated compounds can serve as markers when B. montanum is used in herbal remedies but not as overall responsive markers. The HPLC method developed may be useful for quality control in the production of the extract and for further formulation developments. However, investigation of several associated biological activities is necessary before the development can proceed further. Minor active compounds should be isolated and a more sensitive analytical method should be developed to detail the key responsive components of the ethanolic extract of B. montanum root.
Keyphrases
  • anti inflammatory
  • oxidative stress
  • quality control
  • ms ms
  • simultaneous determination
  • cancer therapy
  • liquid chromatography
  • infectious diseases