A urine-based DNA methylation assay to facilitate early detection and risk stratification of bladder cancer.
Weimei RuanXu ChenMing HuangHong WangJiaxin ChenZhixin LiangJingtong ZhangYanqi YuShang ChenShizhong XuTianliang HuXia LiYuanjie GuoZeyu JiangZhiwei ChenJian HuangTianxin LinJian-Bing FanPublished in: Clinical epigenetics (2021)
The urine-based DNA methylation assay represents a highly sensitive and specific approach for BC early-stage detection and risk stratification. It has a potential to be used as a routine test to improve diagnosis and prognosis of BC in clinic.
Keyphrases
- dna methylation
- early stage
- high throughput
- genome wide
- gene expression
- primary care
- label free
- clinical practice
- loop mediated isothermal amplification
- copy number
- sentinel lymph node
- real time pcr
- squamous cell carcinoma
- radiation therapy
- fluorescent probe
- lymph node
- climate change
- neoadjuvant chemotherapy
- rectal cancer
- high resolution
- muscle invasive bladder cancer