Electrochemical trifluoroalkylation/annulation for the synthesis of CF 3 -functionalized tetrahydroquinolines and dihydroquinolinones.

Tuning the electronic structure of protecting groups on the nitrogen atom of substrates has emerged as an effective strategy to achieve the tandem trifluoromethylation/C(sp 2 )-H annulation using Langlois' reagent as the CF 3 source for the electrochemical synthesis of functionalized tetrahydroquinolines and dihydroquinolinones.