Metabolism-Related Gene Expression in Circulating Tumor Cells from Patients with Early Stage Non-Small Cell Lung Cancer.
A ZafeiriadouI KolliasT LondraE TsarouchaVassilis GeorgouliasAthanasios ΚotsakisEvi S LianidouAthina N MarkouPublished in: Cancers (2022)
An overexpression of MRGs was observed at a high frequency in the CTCs isolated from early NSCLC patients, thereby supporting the role of MRGs in metastatic processes. The glycolytic and mesenchymal subpopulation of CTCs was significantly predominant compared to CTCs that were glycolytic but not mesenchymal-like. Our data indicate that MRGs merit further evaluation through large and well-defined cohort studies.
Keyphrases
- circulating tumor cells
- high frequency
- gene expression
- early stage
- small cell lung cancer
- end stage renal disease
- transcranial magnetic stimulation
- circulating tumor
- stem cells
- bone marrow
- newly diagnosed
- ejection fraction
- chronic kidney disease
- squamous cell carcinoma
- cell proliferation
- machine learning
- transcription factor
- big data
- patient reported outcomes