Detection of Mycobacterium leprae DNA in clinical and environmental samples using serological analysis and PCR.
Ismênia Glauce de Oliveira Barreto da SilveiraJorge Alves da Silva NetoJéssica da Silva FerreiraTatiane Severo SilvaIoná Santos Araújo HolandaPublished in: Molecular biology reports (2021)
In this study, the serological and PCR analysis were capable of detecting M. leprae DNA in clinical samples but not in the environmental samples. Close monitoring of patients and household contacts appears an effective measure to reduce the transmission of leprosy in endemic areas.