To weight or not to weight? Studying the effect of selection bias in three large EHR-linked biobanks.

Maxwell Salvatore Ritoban Kundu Shi Xu Christopher R Friese Seunggeun Lee Lars G Fritsche Alison M MondulDavid HanauerCeleste Leigh Pearce Bhramar Mukherjee

Published in: medRxiv : the preprint server for health sciences (2024)

EHR-linked biobanks should report recruitment and selection mechanisms and provide selection weights with defined target populations. Researchers should consider their intended estimands, specify source and target populations, and weight EHR-linked biobank analyses accordingly.

Keyphrases

electronic health record
body mass index
weight loss
physical activity
weight gain
body weight