Role of FDG-PET/CT in children with fever of unknown origin.

Jordy P PijlThomas C KweeG E LeggerHelja J H PetersWineke ArmbrustE H SchölvinckAndor W J M Glaudemans

Published in: European journal of nuclear medicine and molecular imaging (2020)

FDG-PET/CT is a valuable diagnostic tool in the evaluation of children with FUO, since it may detect a true underlying cause in almost half (48%) of all cases where none was found otherwise. It allows full-body evaluation in patients without disease-specific symptoms on one examination. CRP and leukocyte count were significantly associated with FDG-PET/CT results, which may contribute to a priori assessment on the outcome of FDG-PET/CT. Future research could be aimed at evaluating more patient-specific factors to prospectively estimate the added value of FDG-PET/CT in children with FUO.

Keyphrases

young adults
end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
prognostic factors
physical activity
sleep quality
patient reported outcomes