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Sex-specific differences in outcome and risk stratification of ventricular arrhythmias in implantable cardioverter defibrillator patients.

Anne-Lotte C J van der LingenDominic A M J TheunsMischa T RijnierseMarthe A J BeckerPeter M van de VenAlbert C van RossumVokko P van HalmMichiel J B KemmeSing C YapCornelis P Allaart
Published in: ESC heart failure (2021)
Male ICD patients were at higher risk of ADT and death compared with female ICD patients, irrespective of an ischaemic or non-ischaemic underlying cardiomyopathy. Our study highlights the importance to stratify outcomes of ICD trials by sex, as study results differ between men and women. However, none of the available clinical parameters showed a clear sex-specific relation to ventricular arrhythmias. As a consequence, sex-specific risk stratification models of SCD using commonly available clinical parameters could not be derived.
Keyphrases
  • end stage renal disease
  • ejection fraction
  • newly diagnosed
  • heart failure
  • chronic kidney disease
  • type diabetes
  • prognostic factors
  • left ventricular
  • metabolic syndrome
  • skeletal muscle
  • patient reported