Clinical characteristics and molecular analysis of hepatitis B virus reactivation in hepatitis B surface antigen-negative patients during or after immunosuppressive or cytotoxic chemotherapy.

Kazuhiko HayashiMasatoshi IshigamiYoji IshizuTeiji KuzuyaTakashi HondaYoshihiko TachiTetsuya IshikawaYoshiaki KatanoKentaro YoshiokaHidenori ToyodaTakashi KumadaHidemi GotoYoshiki Hirooka

Published in: Journal of gastroenterology (2016)

Reactivation risk factors included male sex, advanced age, and hematological malignancy. HBV S gene immune-escape mutants were frequently found in the HBsAg-negative reactivation patients during or after immunosuppressive or cytotoxic chemotherapy.

Keyphrases

hepatitis b virus
end stage renal disease
risk factors
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
peritoneal dialysis
liver failure
gene expression
radiation therapy
dna methylation
locally advanced
patient reported
anti inflammatory