Quantitative imaging of bone remodeling in patients with a unicompartmental joint unloading knee implant (ATLAS Knee System)-effect of metal artifacts on a SPECT-CT-based quantification.
Oliver S GrosserMarcus KlutznyHeiko WisselDennis KupitzMichael FingerSimone SchenkeJan WuestemannChristoph H LohmannChristoph HoeschenMaciej PechChristian StaerkeMichael C KreisslPublished in: EJNMMI physics (2021)
The results of this study demonstrate the need for the evaluation of SPECT-CT protocols in prosthesis imaging. Phantom experiments demonstrated the possibility for quantitative SPECT-CT of bone turnover in a specific prosthesis design. Meanwhile, a systematic bias caused by metal implants on quantitative SPECT data has to be considered.
Keyphrases
- image quality
- high resolution
- dual energy
- total knee arthroplasty
- computed tomography
- pet ct
- soft tissue
- bone mineral density
- contrast enhanced
- positron emission tomography
- knee osteoarthritis
- magnetic resonance imaging
- postmenopausal women
- bone loss
- magnetic resonance
- body composition
- single cell
- mass spectrometry
- machine learning
- bone regeneration
- anterior cruciate ligament
- big data
- photodynamic therapy
- fluorescence imaging
- data analysis