KM-408, a novel phenoxyalkyl derivative as a potential anticonvulsant and analgesic compound for the treatment of neuropathic pain.

Anna M WaszkielewiczHenryk MaronaKatarzyna Pańczyk-StraszakBarbara FilipekAnna RapaczKinga SałatMonika KubackaAgnieszka CiosFilip FedakMaria WalczakUrszula HubickaAnna KwiecieńBarbara Żuromska-WitekPrzemysław W SzafrańskiPaulina Koczurkiewicz-AdamczykElżbieta PękalaKatarzyna Przejczowska-PomiernyKrzysztof PociechaElżbieta Wyska

Published in: Pharmacological reports : PR (2022)

Within the presented study a novel compound, R,S-2-((2-(2-chloro-6-methylphenoxy)ethyl)amino)butan-1-ol hydrochloride (KM-408) with dual antiseizure and analgesic activity has been developed for potential use in neuropathic pain treatment.

Keyphrases

neuropathic pain
spinal cord
spinal cord injury
combination therapy
human health
smoking cessation