A different type of acute myocarditis: a case report of acute autoimmune myocarditis mediated by anti-PD-1 T lymphocyte receptor (pembrolizumab).

Mario Salido IniestaLaura López LópezFrancesc Carreras Costa Alessandro Sionis

Published in: European heart journal. Case reports (2020)

Acute autoimmune myocarditis related to ICIs is a challenging diagnosis and its incidence has been underestimated in early studies. Endomyocardial biopsy (EMB) is the gold standard test for its diagnosis. Nevertheless, a definite myocarditis diagnosis is possible without EMB when characteristic clinical syndrome, elevated myonecrosis markers, and electrocardiographic, echocardiographic, and CMR changes are present together.

Keyphrases

liver failure
drug induced
respiratory failure
aortic dissection
multiple sclerosis
left ventricular
hepatitis b virus
pulmonary hypertension
risk factors
ultrasound guided
atrial fibrillation