Observed-over-Expected analysis as additional method for pharmacovigilance signal detection in large-scaled spontaneous adverse event reporting.

Meiwen D X van der Boom Rike van Eekeren Florence P A M van Hunsel

Published in: Pharmacoepidemiology and drug safety (2023)

The O/E method is a useful approach for signal detection of potential adverse reactions when handling large numbers of ICSRs. Further research is needed to attest to the causality on a clinical basis.

Keyphrases

adverse drug
loop mediated isothermal amplification
real time pcr
label free
emergency department
electronic health record
climate change