Effect of Aqueous Extract of Phenolic Compounds Obtained from Red Wine in Experimental Model of Colitis in Mice.
Vanessa MateusJoão EstarrejaInês SilvaFernando GonçalvesEdite Teixeira LemosRui PintoPublished in: Current issues in molecular biology (2022)
The extract demonstrated an anti-inflammatory effect, reducing TNF-α levels in the colon, and had a beneficial effect on the extraintestinal manifestations related to IBD, without any significant side effects. The extract of phenolic compounds demonstrated to be a valuable object of study for the management of IBD in the future.