Salvianolic acid B ameliorates myocardial fibrosis in diabetic cardiomyopathy by deubiquitinating Smad7.

Hong LuoLingyun FuXueting Wangnull Yini Xunull Ling TaoXiang-Chun Shen

Published in: Chinese medicine (2023)

This study revealed that Sal B can improve myocardial fibrosis in DCM by deubiquitinating Smad7, stabilizing the protein expression of Smad7, and blocking the TGF-β1 signaling pathway.

Keyphrases

transforming growth factor
epithelial mesenchymal transition
signaling pathway
left ventricular
heart failure
type diabetes
pi k akt
single cell
oxidative stress
wound healing