Risk Stratification Tools to Aid Decisions on Adjuvant Chemotherapy Usage in Resected Soft Tissue Sarcomas: A Ten-Year Review of an Irish Sarcoma Center Experience.
Catherine S WeadickCaitriona GogginRachel J KeoghJake F MurphyLinda FeeleyMichael W BennettSeamus O'ReillyH Paul RedmondJason KellyDeirdre O'MahonySinead NoonanA James P CloverRichard M BamburyPublished in: World journal of oncology (2024)
Our cohort is representative of the broad histological subtypes expected. In our population, Sarculator score results correlate with international outcomes and higher scores were associated with increased mortality. The Sarculator was more predictive of clinical outcome than AJCC staging, and its use would lower the proportion of patients being considered for adjuvant chemotherapy thereby sparing toxicity, which is important in the setting of uncertain clinical benefit.
Keyphrases
- end stage renal disease
- lymph node
- soft tissue
- prognostic factors
- ejection fraction
- newly diagnosed
- chronic kidney disease
- peritoneal dialysis
- oxidative stress
- type diabetes
- coronary artery disease
- cardiovascular events
- high grade
- risk factors
- metabolic syndrome
- cardiovascular disease
- primary care
- skeletal muscle
- robot assisted
- adipose tissue
- patient reported