Diffuse brain connectivity changes in Charcot-Marie-Tooth type 1a patients: a resting-state functional magnetic resonance imaging study.

Giuseppe PontilloS TozzaT PerilloSirio CocozzaR DubbiosoD SeveriR IodiceE TedeschiA ElefanteA BrunettiFiore Manganelli Mario Quarantelli

Published in: European journal of neurology (2020)

Our data show evidence of diffuse functional reorganization involving multiple large-scale networks in the CMT1A brain, independent of structural modifications and partially correlating with peripheral nerve damage and functional impairment.

Keyphrases

resting state
functional connectivity
peripheral nerve
magnetic resonance imaging
end stage renal disease
white matter
chronic kidney disease
ejection fraction
low grade
newly diagnosed
peritoneal dialysis
prognostic factors
electronic health record
machine learning
brain injury