Mitochondrial hypoxic stress induces widespread RNA editing by APOBEC3G in natural killer cells.
Shraddha SharmaJianmin WangEmad AlqassimScott PortwoodEduardo Cortes GomezOrla MaguirePer H BasseEunice S WangBrahm H SegalBora E BaysalPublished in: Genome biology (2019)
APOBEC3G is an endogenous RNA editing enzyme in primary natural killer cells and lymphoma cell lines. This RNA editing is induced by cellular crowding and mitochondrial respiratory inhibition to promote adaptation to hypoxic stress.